BEHCET'S DISEASE: A STUDY DONE AT KING HUSSEIN MEDICAL CENTER, AMMAN – JORDAN

Abstract

Behçet's disease (BD) is a chronic, inflammatory, multisystem disorder. Pathogenesis is not exactly known. The aim of this study was to analyze the clinical and laboratory data for patients with Behcet's disease seen at King Hussein Medical Centre.

Forty four patients were diagnosed to have BD between 2013 and 2016. The diagnosis was made on the basis of the clinical criteria of the international study group for BD. Clinical and laboratory information was retrieved and analyzed from the clinical records of all patients at Princess Eman Center for Research and Laboratory Science, King Hussein Medical Center/ Royal Medical Services, Amman – Jordan.

Forty-four patients (23 males, 21 females), mean age of 31 years were diagnosed with BD. 100% of the patients had oral ulcers. 79% patients had genital ulcers. 70% of the patients in this study sample were HLA-B51 carriers.

As there were no single specific manifestations or specific diagnostic tests, diagnosis relied on clinical features. However, with the diversity of signs and symptoms, immunological studies especially detection of HLA-B51 was considered a major supportive measure for the diagnosis of Behcet’s disease.